The AI-powered equity trading venue was ranked 21 at the start of 2020 and has reached number nine.
Regulation is likely to continue this year under a Democratic administration.
UK and US authorities are co-operating on the transition to new risk-free rates.
The SEC enhanced Rule 606 reporting requirements on order routing last May.
Regulatory reporting demands will continue to grow rapidly around the globe.
The firm has a long-term plan to launch a suite of Blockchain Transferred Funds, or BTFs.
Libor publication could stop by the end of this year.
More than 40% of overall U.S. equities trading volume was off-exchange last year.
REGIS-TR UK is regulated by the FCA and is based in the London offices of Clearstream.